Novartis states that Vanrafia can slow the decline of kidney function in patients with IgA nephropathy.

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Investing.com – Novartis announced on Friday that its drug Vanrafia has demonstrated efficacy in slowing the decline of kidney function in adults with IgA nephropathy (IgAN), a progressive autoimmune kidney disease.

The Swiss pharmaceutical company reported that phase three clinical trials showed Vanrafia improved the glomerular filtration rate in patients with the disease.

IgAN causes inflammation of the small filters in the kidneys and leads to excessive protein in the urine, a condition known as proteinuria.

Vanrafia received accelerated approval in the United States and China in 2025 for the treatment of proteinuria in adult IgAN patients.

Following these positive trial results, Novartis plans to submit a traditional approval application for the drug in 2026.

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