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AI genome model successfully synthesizes virus, triggering discussions on biosafety.
On September 27 (UTC+8), scientists from Stanford and the Arc Institute used AI "genome language models" named Evo 1 and Evo 2 in an experiment to design and synthesize 302 viral genomes from scratch, of which 16 successfully survived in the laboratory, capable of infecting E. coli and possessing replication and evolution abilities. Some of the synthesized bacteriophages even outperformed their natural prototype, the ΦX174 virus. Researchers stated that this achievement could bring breakthroughs in customized phage therapy and represents an important milestone in synthetic biology, but it also sparked discussions on the potential risks and governance of generative biology.